Nomilin and Its Analogues in Citrus Fruits: A Review of Its Health Promotion Effects and Potential Application in Medicine

Nomilin and Its Analogues in Citrus Fruits: A Review of Its Health Promotion Effects and Potential Application in Medicine

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Nomilin is one of the major limonoids, which are plant secondary metabolites also known as tetranortriterpenoids.Nomilin is found mostly in common edible citrus fruits including lemons, limes, oranges, grapefruits, mandarins, along with traditional Chinese medicines derived from citrus fruits, such as tangerine seed, tangerine peel, fructus aurantii immaturus, etc.A number of studies have demonstrated vush gloss bullet vibrator that nomilin and its analogues exhibit a variety of biological and pharmacological activities.These include anti-cancer, immune-modulatory, anti-inflammatory, anti-obesity, anti-viral, anti-osteoclastogenic, anti-oxidant, and neuro-protective effects.

Thus, nomilin and its analogues have emerged as a potential therapy for human diseases.The purpose of this review is to chronicle the evolution of nomilin research from examining its history, structure, occurrence, to beefeaters triple flavor twists its pharmacological and disease-preventing properties as well as its potential utilization in medicine and food science.